NASHVILLE, Tenn. (WKRN) – A portion of Interstate 40 was closed after a tractor-trailer overturned and blocked lanes of traffic early Tuesday morning.

The crash happened just before 2 a.m. in the westbound lanes of I-40 at the I-65 spilt near exit 208B. 

Officials believe the truck was hauling medications the time of the crash. 

📧 Have breaking come to you: Subscribe to News 2 email alerts

It remains unknown if anyone was injured in the crash and the roadway reopened hours after the crash was reported.

Motorists in West Nashville were advised to use Charlotte Pike as an alternate route. Those coming from the south of Nashville were advised to use I-440 to get over to I-40 West to avoid the crash.

📲 Download the News 2 app to stay updated on the go.
📧 Sign up for WKRN email alerts to have breaking news sent to your inbox.
💻 Find today’s top stories on for Nashville, TN and all of Middle Tennessee.

This is a developing story. WKRN News 2 will continue to update this article as new information becomes available.